Carolina Vein Institute also offers dermal fillers. Fillers are different from Botox in that they address lost facial volume. Over time, your skin loses elasticity. This is a natural process. Genetics and environmental factors like sun exposure can cause moderate to severe lines and folds such as parentheses, corner and marionette lines to form around the nose and mouth. Fillers are a gel-like substance such as hyaluronic acid. Once these solutions enter your body, they restore lost volume, smooth lines and soften creases. Dermal fillers can also enhance your facial contours.